BRIEF ABSTRACT

Journal Name: Contraception Volume 77, Issue 6,

Title: Incomplete pregnancy is not associated with breast cancer risk: the California Teachers Study

Authors: Henderson KD, Sullivan-Halley J, Reynolds P, Horn-Ross PL, Clarke CA, Chang ET, Neuhausen S, Ursin G, Bernstein L. contact: KHenderson@coh.org

Abstract:

Background

Early studies of previous termincomplete pregnancynext term and development of breast cancer suggested that induced abortion might increase risk. Several large prospective studies, which eliminate recall bias, did not detect associations, but this relationship continues to be debated.

Study Design

To further inform this important question, we examined invasive breast cancer as it relates to previous termincomplete pregnancy,next term including total number of induced abortions, age at first induced abortion and total number of miscarriages among women participating in the ongoing California Teachers Study (CTS) cohort. previous termIncomplete pregnancynext term was self-reported on the CTS baseline questionnaire in 1995–1996. Incident breast cancers were ascertained in 3324 women through 2004 via linkage with the California Cancer Registry.

Results

Using Cox multivariable regression, we found no statistically significant association between any measure of previous termincomplete pregnancynext term and breast cancer risk among nulliparous or parous women.

Conclusion

These results provide strong evidence that there is no relationship between previous termincomplete pregnancynext term and breast cancer risk.

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